GCC BOSC 2018 has ended
The 2018 Galaxy Community Conference (GCC2018) and Bioinformatics Open Source Conference 2018 (BOSC2018) are meeting together in Portland, Oregon, United States, June 25-30, 2018.  There will be two days of training, a two+ day meeting, and four days of intense collaboration.  The meeting features joint & parallel sessions, shared keynotes, poster & demo sessions, birds-of-a-feather, and social events.  GCCBOSC is organized by Oregon Health & Science University and will be at Reed College.

avatar for Arthur Eschenlauer

Arthur Eschenlauer

University of Minnesota
Twin Cities, MN
Poster Abstract:
Untargeted metabolomics contrasts metabolome-scale analyses of samples without first identifying individual metabolites. Workflow4Metabolomics (W4m) provides a suite of Galaxy tools for untargeted metabolomics including univariate and multivariate statistical tools and tools for preprocessing LC-MS, GC-MS, and NMR spectra. W4m Data Subset (w4mclassfilter) conditions data for statistical analysis by providing:
- feature- and sample-selection;
- metadata-filtering;
- intensity-thresholding;
- log-transformation;
- elimination of zero-variance data;
- imputation of missing values to zero.

We have created four additional tools to simplify or extend the use of W4m in our lab: W4m Data Subset, OPLS-DA Contrasts, Join +/- Ions, and w4mkmeans. We have also "adopted" the Query Tabular tool to further simplify and extend our data workflows. The tools are available in the public Galaxy Toolshed.
We demonstrate how these tools complement W4m with a data-processing workflow assessing the effect of pathogen inoculation on resin-collection by honey bee colonies.